Core B Publications 

Recent Papers

Burmistrov V, Morisseau C, D'Yachenko V, Karlov D, Butov GM, Hammock BD. 2020. Imidazolidine-2,4,5- and pirimidine-2,4,6-triones – New primary pharmacophore for soluble epoxide hydrolase inhibitors with enhanced water solubility. Bioorganic & Medicinal Chemistry Letters. 30(3):126908.

Burmistrov V, Morisseau C, D’yachenko V, Rybakov VB, Butov GM, Hammock BD. Fluoroaromatic fragments on 1,3-disubstituted ureas enhance soluble epoxide hydrolase inhibition. Journal of Fluorine Chemistry. 2019. doi:

Codony S, Valverde E, Leiva R, Brea J, Isabel Loza M, Morisseau C, Hammock BD, Vázquez S. 2019. Exploring the size of the lipophilic unit of the soluble epoxide hydrolase inhibitors. Bioorganic & Medicinal Chemistry. 27(20):115078.

de Oliveira GS, Adriani PP, Ribeiro JA, Morisseau C, Hammock BD, Dias MVB, Chambergo FS. 2019. The molecular structure of an epoxide hydrolase from Trichoderma reesei in complex with urea or amide-based inhibitors. Int J Biol Macromol. 129:653-8. doi: 10.1016/j.ijbiomac.2019.02.070.

Duflot, T., et al. (2019). "Altered bioavailability of epoxyeicosatrienoic acids is associated with conduit artery endothelial dysfunction in type 2 diabetic patients." Cardiovascular Diabetology 18(1): 35.


Faber, S. C., Soshilov, A. A., Giani Tagliabue, S., Bonati, L., & Denison, M. S. (2018). Comparative In Vitro and In Silico Analysis of the Selectivity of Indirubin as a Human Ah Receptor Agonist. International journal of molecular sciences, 19(9), 2692.

Hiesinger K, Kramer JS, Achenbach J, Moser D, Weber J, Wittmann SK, Morisseau C, Angioni C, Geisslinger G, Kahnt AS, Kaiser A, Proschak A, Steinhilber D, Pogoryelov D, Wagner K, Hammock BD, Proschak E. 2019. Computer-Aided Selective Optimization of Side Activities of Talinolol. ACS Medicinal Chemistry Letters. 10(6):899-903. doi: 10.1021/acsmedchemlett.9b00075.

Kramer JS, Woltersdorf S, Duflot T, Hiesinger K, Lillich FF, Knoll F, Wittmann SK, Klingler FM, Brunst S, Chaikuad A, Morisseau C, Hammock BD, Buccellati C, Sala A, Rovati GE, Leuillier M, Fraineau S, Rondeaux J, Hernandez-Olmos V, Heering J, Merk D, Pogoryelov D, Steinhilber D, Knapp S, Bellien J, Proschak E. 2019. Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain. J Med Chem. 62(18):8443-8460. 10.1021/acs.jmedchem.9b00445.

Lee KSS, Yang J, Niu J, Ng CJ, Wagner KM, Dong H, Kodani SD, Wan D, Morisseau C, Hammock BD. 2019. Drug-Target Residence Time Affects in Vivo Target Occupancy through Multiple Pathways. ACS Central Science. 5(9):1614-1624. 10.1021/acscentsci.9b00770.

McReynolds CB, Hwang SH, Yang J, Wan D, Wagner K, Morisseau C, Li D, Schmidt WK, Hammock BD. 2019. Pharmaceutical Effects of Inhibiting the Soluble Epoxide Hydrolase in Canine Osteoarthritis. Frontiers in Pharmacology. 10(533). doi: 10.3389/fphar.2019.00533.

Mishra M, Tiwari S, Gunaseelan A, Li D, Hammock BD, Gomes AV. Improving the sensitivity of traditional Western blotting via Streptavidin containing Poly-horseradish peroxidase (PolyHRP). Electrophoresis. 2019. Epub 2019/04/26. 40(12-13):1731-1739. doi: 10.1002/elps.201900059.

Pessah, I. N., et al. (2019). "Neurotoxicity of polychlorinated biphenyls and related organohalogens." Acta Neuropathologica 138(3): 363-387.


Pessah, I. N. and K. M. Truong (2019). "Additional Safety Assessments Needed for Diamide Insecticides." Toxicological Sciences 171(2): 282-282.


Truong, K. M., et al. (2019). "Interactions of Dichlorodiphenyltrichloroethane (DDT) and Dichlorodiphenyldichloroethylene (DDE) With Skeletal Muscle Ryanodine Receptor Type 1." Toxicological Sciences 170(2): 509-524.


Zheng, J., Yu, Y., Feng, W., Li, J., Liu, J., Zhang, C., Dong, Y., Pessah, I. N., & Cao, Z. (2019). Influence of Nanomolar Deltamethrin on the Hallmarks of Primary Cultured Cortical Neuronal Network and the Role of Ryanodine Receptors. Environmental health perspectives, 127(6), 67003.

Zhu M, Wang L, Wu X, Na R, Wang Y, Li QX, Hammock BD. 2019. A novel and simple imidazo[1,2-a]pyridin fluorescent probe for the sensitive and selective imaging of cysteine in living cells and zebrafish. Anal Chim Acta. 1058:155-65. doi: 10.1016/j.aca.2019.01.023.


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