Core A Publications 

Recent Papers

Deol P, Yang J, Morisseau C, Hammock BD, Sladek FM. 2019. Dimethyl Sulfoxide Decreases Levels of Oxylipin Diols in Mouse Liver. Frontiers in Pharmacology. 10(580). doi: 10.3389/fphar.2019.00580.

Dileepan M, Rastle-Simpson S, Greenberg Y, Wijesinghe DS, Kumar NG, Yang J, Hwang SH, Hammock BD, Sriramarao P, Rao SP. 2019. Effect Of Dual sEH/COX-2 Inhibition on Allergen-Induced Airway Inflammation. Frontiers in Pharmacology. 10(1118). 10.3389/fphar.2019.01118.

Gartung A, Yang J, Sukhatme VP, Bielenberg DR, Fernandes D, Chang J, Schmidt BA, Hwang SH, Zurakowski D, Huang S, Kieran MW, Hammock BD, Panigrahy D. 2019. Suppression of chemotherapy-induced cytokine/lipid mediator surge and ovarian cancer by a dual COX-2/sEH inhibitor. Proc Natl Acad Sci U S A. 116(5):1698-703. doi: 10.1073/pnas.1803999116.

Huo J, Barnych B, Li Z, Wan D, Li D, Vasylieva N, Knezevic SZ, Osipitan OA, Scott JE, Zhang J, Hammock BD. Hapten Synthesis, Antibody Development, and a Highly Sensitive Indirect Competitive Chemiluminescent Enzyme Immunoassay for Detection of Dicamba. Journal of Agricultural and Food Chemistry. 2019. doi: 10.1021/acs.jafc.8b07134.

Lee KSS, Yang J, Niu J, Ng CJ, Wagner KM, Dong H, Kodani SD, Wan D, Morisseau C, Hammock BD. 2019. Drug-Target Residence Time Affects in Vivo Target Occupancy through Multiple Pathways. ACS Central Science. 5(9):1614-1624. 10.1021/acscentsci.9b00770.

Liu G, Wu F, Jiang X, Que Y, Qin Z, Hu P, Lee KSS, Yang J, Zeng C, Hammock BD, Tong X. 2020. Inactivation of Cys674 in SERCA2 increases BP by inducing endoplasmic reticulum stress and soluble epoxide hydrolase. British Journal of Pharmacology. 10.1111/bph.14937.

Luo L, Wei X-Q, Jia B-Z, Yang J-Y, Shen Y-D, Hammock B, Dong J-X, Wang H, Lei H-T, Xu Z-L. 2019. Modulating Linker Composition of Haptens Resulted in Improved Immunoassay for Histamine. Biomolecules. 9(10):597.10.3390/biom9100597.

Ma M, Ren Q, Yang J, Zhang K, Xiong Z, Ishima T, Pu Y, Hwang SH, Toyoshima M, Iwayama Y, Hisano Y, Yoshikawa T, Hammock BD, Hashimoto K. 2019. Key role of soluble epoxide hydrolase in the neurodevelopmental disorders of offspring after maternal immune activation. Proc Natl Acad Sci U S A. 116(14):7083-8. doi: 10.1073/pnas.1819234116.

McReynolds CB, Hwang SH, Yang J, Wan D, Wagner K, Morisseau C, Li D, Schmidt WK, Hammock BD. 2019. Pharmaceutical Effects of Inhibiting the Soluble Epoxide Hydrolase in Canine Osteoarthritis. Frontiers in Pharmacology. 10(533). doi: 10.3389/fphar.2019.00533.

Otoki Y, Metherel AH, Pedersen T, Yang J, Hammock BD, Bazinet RP, Newman JW, Taha AY. Acute Hypercapnia/Ischemia Alters the Esterification of Arachidonic Acid and Docosahexaenoic Acid Epoxide Metabolites in Rat Brain Neutral Lipids. Lipids. n/a(n/a). 10.1002/lipd.12197.

Panigrahy D, Gartung A, Yang J, Yang H, Gilligan MM, Sulciner ML, Bhasin SS, Bielenberg DR, Chang J, Schmidt BA, Piwowarski J, Fishbein A, Soler-Ferran D, Sparks MA, Staffa SJ, Sukhatme V, Hammock BD, Kieran MW, Huang S, Bhasin M, Serhan CN, Sukhatme VP. 2019. Preoperative stimulation of resolution and inflammation blockade eradicates micrometastases. The Journal of Clinical Investigation. 129(7). doi: 10.1172/JCI127282.

Ren, Wenjie; Li, Zhenfeng; Xu, Yang; Wan, Debin; Barnych, Bogdan; Li, Yanping; Tu, Zhui; He, Qinghua; Fu, Jinheng; Hammock, Bruce. One-step ultra-sensitive bioluminescent enzyme immunoassay based on nanobody/nano-luciferase fusion for detection of Aflatoxin B1 in cereal. Journal of Agricultural and Food Chemistry. 2019, 67(18), 5221-5229.

Shen Y, Peng W, Chen Q, Hammock BD, Liu J, Li D, Yang J, Ding J, Wang X. 2019. Anti-inflammatory treatment with a soluble epoxide hydrolase inhibitor attenuates seizures and epilepsy-associated depression in the LiCl-pilocarpine post-status epilepticus rat model. Brain, Behavior, and Immunity. 81:535-544. https://doi.org/10.1016/j.bbi.2019.07.014.

Wan D, Yang J, McReynolds CB, Barnych B, Wagner KM, Morisseau C, Hwang SH, Sun J, Blöcher R, Hammock BD. In vitro and in vivo Metabolism of a Potent Inhibitor of Soluble Epoxide Hydrolase, 1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea. Frontiers in pharmacology. 2019;10(464). doi: 10.3389/fphar.2019.00464.

Wang K, Vasylieva N, Wan D, Eads DA, Yang J, Tretten T, Barnych B, Li J, Li QX, Gee SJ, Hammock BD, Xu T. 2019. Quantitative Detection of Fipronil and Fipronil-Sulfone in Sera of Black-Tailed Prairie Dogs and Rats after Oral Exposure to Fipronil by Camel Single-Domain Antibody-Based Immunoassays. Anal Chem. 91(2):1532-40. doi: 10.1021/acs.analchem.8b04653.

Wang W, Yang J, Edin ML, Wang Y, Luo Y, Wan D, Yang H, Song CQ, Xue W, Sanidad KZ, Song M, Bisbee HA, Bradbury JA, Nan G, Zhang J, Shih PB, Lee KSS, Minter LM, Kim D, Xiao H, Liu JY, Hammock BD, Zeldin DC, Zhang G. 2019. Targeted Metabolomics Identifies the Cytochrome P450 Monooxygenase Eicosanoid Pathway as a Novel Therapeutic Target of Colon Tumorigenesis. Cancer Res. 79(8):1822-30. doi: 10.1158/0008-5472.Can-18-3221.

Wang Y, Li Z, Barnych B, Huo J, Wan D, Vasylieva N, Xu J, Li P, Liu B, Zhang C, Hammock BD. 2019. Investigation of the Small Size of Nanobodies for a Sensitive Fluorescence Polarization Immunoassay for Small Molecules: 3-Phenoxybenzoic Acid, an Exposure Biomarker of Pyrethroid Insecticides as a Model. Journal of Agricultural and Food Chemistry. 10.1021/acs.jafc.9b04621.

Xia, R.; Sun, L.; Liao, J.; Li, H.; You, X.; Xu, D.; Yang, J.; Hwang, S. H.; Jones, R. D.; Hammock, B.; Yang, G. Y., Inhibition of Pancreatic Carcinoma Growth Through Enhancing omega-3 Epoxy Polyunsaturated Fatty Acid Profile by Inhibition of Soluble Epoxide Hydrolase. Anticancer Res 2019, 39 (7), 3651-3660.

Yang J, Bruun DA, Wang C, Wan D, Reynolds CB, Phu K, Inceoglu B, Lein PJ, Hammock BD. 2019. Lipidomes of brain from rats acutely intoxicated with diisopropylfluorophosphate identifies potential therapeutic targets. Toxicol Appl Pharmacol.114749. 10.1016/j.taap.2019.114749.

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